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CyFlow™ CD3 PerCP-Cy5.5

CyFlow™ CD3 PerCP-Cy5.5
Application: Flow cytometry
Clone: 145-2C11
Excitation Maximum: 482 nm
Format/Fluorochrome: PerCP-Cy5.5
Field of Interest: Immunophenotyping, MHC
Source Species: Hamster
Isotype: IgG
Target Species: Mouse
Alternative Name: Leu4, T3
Clonality: monoclonal
Antigen: CD3
Laser: Blue, Green
Regulatory Status: RUO
Emission Maximum: 695 nm
Order number: BJ628650
Concentration Unit mg/mL Concentration 0,5 Quantity 0.1 mg Volume 0.2 mL... more
Product information "CyFlow™ CD3 PerCP-Cy5.5"
Concentration Unitmg/mL
Concentration0,5
Quantity0.1 mg
Volume0.2 mL
ImmunogenMouse BM10-37 cytotoxic T lymphocytes
Background InformationCD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
UsageThe reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Technical Data Sheet

Certificate Of Analysis

ECDoC

Instruction for Use

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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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